Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439914 | 0.88 | ALDH1A1 (0.32) | MAPTALDH1A1PKMSMN1; SMN2MEN1 | |
| SCHEMBL15439570 | 0.87 | SMN1; SMN2 (0.31) | ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL15439972 | 0.82 | CYP2A6 (0.33) | — | |
| SCHEMBL15440392 | 0.77 | MEN1 (0.38) | MAPTGAARAB9AALDH1A1NPC1 | |
| SCHEMBL15439378 | 0.77 | CYP2A6 (0.33) | — | |
| SCHEMBL15440585 | 0.76 | MEN1 (0.32) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL15438754 | 0.75 | MAPT (0.34) | MAPTGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL15438753 | 0.75 | MAPT (0.34) | MAPTGAARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL15440176 | 0.75 | MAPT (0.40) | MAPTGAARAB9AALDH1A1KMT2A | |
| SCHEMBL15439948 | 0.72 | CFTR (0.34) | ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |