Sugi Predict

Sugi Predict / Compounds / Dimethylamine

Dimethylamine

Dimethylamine

SCHEMBL15440642

CNC.OC1c2ccccc2-c2ccccc21

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.44
▸ MAOB P27338 1/20 0.44
▸ GPR3 P46089 1/20 0.44
▸ KMT2A Q03164 4/20 0.44
▸ MEN1 O00255 3/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ TP53 P04637 1/20 0.44
▸ CYP3A4 P08684 1/20 0.44
▸ CYP2D6 P10635 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44
▸ HDAC3 O15379 1/20 0.43
▸ HDAC4 P56524 1/20 0.43
▸ HDAC7 Q8WUI4 1/20 0.43
▸ HDAC8 Q9BY41 1/20 0.43
▸ HDAC6 Q9UBN7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376368 0.89 MAOA (0.52) MAOAMAOBGPR3KMT2AMEN1
SCHEMBL216862 0.89 MAOA (0.52) MAOAMAOBGPR3KMT2AMEN1
SCHEMBL29884836 0.89 MAOA (0.52) MAOAMAOBGPR3KMT2AMEN1
SCHEMBL27688305 0.87 MAOA (0.50) MAOAMAOBGPR3KMT2AMEN1
Formaldehyde SCHEMBL28887991 0.82 HTR2B (0.47) MAOAMAOBGPR3KMT2AMEN1
SCHEMBL12408141 0.80 PDK2 (0.50) MAOAMAOBGPR3KMT2AMEN1
SCHEMBL29539148 0.80 PDK2 (0.50) MAOAMAOBGPR3KMT2AMEN1
SCHEMBL18385982 0.80 HTR2B (0.50) MAOAMAOBGPR3KMT2AMEN1
Formic Acid SCHEMBL28466728 0.78 HTR2B (0.45) MAOAMAOBGPR3KMT2AMEN1
Fluorene SCHEMBL7203740 0.76 MAOA (0.48) MAOAMAOBKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110461157-A Herbicidal mixture BAYER AG 2019-11-15 — — CN claimed
CN-113677665-B Substituted 2-heteroarylaminobenzenes and salts thereof, and their use as herbicides 拜耳公司 2024-07-16 — — CN disclosed
CN-118317956-A Bis (hetero) aryl thioether oxadiazines as fungicidal compounds 拜耳公司 2024-07-09 — — CN disclosed
CN-114364663-B Substituted thiophenecarboxamides and derivatives thereof as microbiocides 拜耳公司 2024-07-05 — — CN disclosed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 — — CN disclosed
CN-118159536-A Substituted 1,2, 4-thiadiazolyl nicotinamide, salts or N-oxides thereof and their use as herbicidal active substances 拜耳公司 2024-06-07 — — CN disclosed
CN-118102874-A Active compound combinations and fungicide compositions comprising them 拜耳公司 2024-05-28 — — CN disclosed
CN-113544124-B Herbicidal substituted N-tetrazolylarylamides 拜耳公司 2024-05-28 — — CN disclosed
CN-118042930-A Compositions comprising different drift retardants 拜耳作物科学有限合伙公司 2024-05-14 — — CN disclosed
WO-2024074126-A1 4-METHYLSULFONYLBENZAMIDE COMPOUND, PREPARATION METHOD, HERBICIDAL COMPOSITION, AND USE 江苏中旗科技股份有限公司 2024-04-11 — — WO disclosed
CN-110461833-A 2- amino -5- oxygroup alkyl derivative and its purposes for preventing and treating undesirable plant growth BAYER CROPSCIENCE AG 2019-11-15 — — CN disclosed
CN-110461157-A Herbicidal mixture BAYER AG 2019-11-15 — — CN disclosed
CN-110337436-A Substituted 1,2,4- thiadiazolyl group pyrrolones and 1,2,4- thiadiazolyl group hydantoins and its salt and its purposes as herbicide 拜耳作物科学股份公司 2019-10-15 — — CN disclosed
CN-110267950-A Substituted heteroaryl pyrrolones and its salt and its purposes as herbicidal active compounds 拜耳作物科学股份公司 2019-09-20 — — CN disclosed
CN-109790150-A Substituted pyrazolinyl derivative, preparation method and its purposes as herbicide and/or plant growth regulator 拜耳作物科学股份公司 2019-05-21 — — CN disclosed
CN-104994737-A Herbicidal combinations for tolerant soybean cultures BAYER CROPSCIENCE AG 2015-10-21 — — CN disclosed
EP-2877013-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID Dow AgroSciences LLC (US) 2015-06-03 — — EP disclosed
US-8883682-B2 Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and auxin transport inhibitors DOW AGROSCIENCES, LLC. (US) 2014-11-11 — — US disclosed
WO-2014018405-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL) PYRIDINE-2-CARBOXYLIC ACID DOW AGROSCIENCES LLC (US) 2014-01-30 — — WO disclosed
US-20140031217-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND AUXIN TRANSPORT INHIBITORS DOW AGROSCIENCES LLC (US) 2014-01-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140031217-A1 HERBICIDAL COMPOSITIONS COMPRISING 4-AMINO-3-CHLORO-5-FLUORO-6-(4-CHLORO-2-FLUORO-3-METHOXYPHENYL)PYRIDINE-2-CARBOXYLIC ACID OR A DERIVATIVE THEREOF AND AUXIN TRANSPORT INHIBITORS CYP4F3, CYP4F2, CYP2F1 MAOA 851/4885MAOB 1559/4885GPR3 1399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.