Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.79 |
| ▸ | MAPT | P10636 | 11/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.79 |
| ▸ | NPC1 | O15118 | 9/20 | 0.79 |
| ▸ | GAA | P10253 | 9/20 | 0.79 |
| ▸ | RAB9A | P51151 | 8/20 | 0.79 |
| ▸ | GLA | P06280 | 5/20 | 0.79 |
| ▸ | GFER | P55789 | 5/20 | 0.79 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.79 |
| ▸ | RECQL | P46063 | 2/20 | 0.79 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.76 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.76 |
| ▸ | HPGD | P15428 | 9/20 | 0.74 |
| ▸ | POLB | P06746 | 8/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.74 |
| ▸ | BLM | P54132 | 4/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443910 | 0.94 | MEN1 (0.77) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15443953 | 0.89 | MEN1 (0.87) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL28312335 | 0.89 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL363703 | 0.89 | MEN1 (1.00) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9862039 | 0.89 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL159873 | 0.89 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30307784 | 0.89 | ALDH1A1 (0.74) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL15443952 | 0.88 | PRMT1 (0.75) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL38658270 | 0.88 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6325549 | 0.88 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140066629-A1 | PROCESS FOR THE PREPARATION OF AROMATIC AZOLE COMPOUNDS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-03-06 | — | — | US | disclosed |
| US-20140066629-A1 | PROCESS FOR THE PREPARATION OF AROMATIC AZOLE COMPOUNDS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-03-06 | — | — | US | disclosed |
| US-20140066629-A1 | PROCESS FOR THE PREPARATION OF AROMATIC AZOLE COMPOUNDS | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-03-06 | — | — | US | disclosed |
| US-20140024753-A1 | LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY ELEMENT | CHI MEI CORPORATION (TW) | 2014-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066629-A1 | PROCESS FOR THE PREPARATION OF AROMATIC AZOLE COMPOUNDS | PAH, PNPO, ARSA | MEN1 3634/4885KMT2A 1569/4885ALDH1A1 2653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.