Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 9/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 7/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3090467 | 0.80 | PTGDR2 (0.54) | PTGDR2PTGDRTBXA2RCYP2C9CYP3A4 | |
| SCHEMBL3083458 | 0.80 | PTGDR2 (0.54) | PTGDR2PTGDRTBXA2RCYP2C9CYP3A4 | |
| SCHEMBL204983 | 0.78 | PTGDR2 (0.53) | PTGDR2PTGDRTBXA2RCYP2C9CYP3A4 | |
| SCHEMBL15025403 | 0.78 | PTGDR2 (0.53) | PTGDR2PTGDRTBXA2RCYP2C9CYP3A4 | |
| SCHEMBL3089889 | 0.78 | PTGDR2 (0.53) | PTGDR2PTGDRTBXA2RCYP2C9CYP3A4 | |
| SCHEMBL15428828 | 0.74 | PTGDR2 (0.60) | PTGDR2PTGDRTBXA2RCYP2C9CYP3A4 | |
| SCHEMBL3088522 | 0.73 | PTGDR2 (0.64) | PTGDR2PTGDRTBXA2RCYP2C9CYP3A4 | |
| SCHEMBL3085507 | 0.72 | PTGDR2 (0.49) | PTGDR2PTGDRTBXA2RCYP2C9 | |
| SCHEMBL3091558 | 0.71 | PTGDR2 (0.54) | PTGDR2PTGDRTBXA2RCYP2C9CYP3A4 | |
| SCHEMBL3099692 | 0.71 | PTGDR2 (0.46) | PTGDR2PTGDRTBXA2RCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401269-B1 | INDOLE DERIVATIVES AS CRTH2 RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2014-01-29 | — | — | EP | disclosed |