SCHEMBL15445018

CCC(/C=C/C(=O)O)=C\[C@@H](O)C[C@H](C)C[C@@H](C)CC[C@H](O)[C@H](C)C(=O)C[C@@H](O)[C@H](C)[C@@H](C)OC(=O)C[C@@H](O)C1=C(C)C(=O)OC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	PPP2CA	P67775	7/20	1.00

▸	PPP5C	P53041	2/20	0.71

▸	ALDH1A1	P00352	1/20	0.71

▸	THRB	P10828	1/20	0.71

▸	HPGD	P15428	1/20	0.71

▸	PPP1CC	P36873	1/20	0.71

▸	PTPN11	Q06124	2/20	0.62

▸	PTPA	Q15257	2/20	0.36

▸	PTPN1	P18031	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15445017	1.00	PPP2CA (1.00)	PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15381932	1.00	PPP2CA (1.00)	PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15444942	0.95	PPP2CA (0.90)	PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15444944	0.95	PPP2CA (0.90)	PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15381940	0.95	PPP2CA (0.90)	PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15444945	0.95	PPP2CA (0.90)	PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL889307	0.94	PPP2CA (0.89)	PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15381934	0.91	PPP2CA (1.00)	PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL15382081	0.90	PPP2CA (1.00)	PPP2CAPPP5CALDH1A1THRBHPGD
SCHEMBL823120	0.89	PPP2CA (0.80)	PPP2CAPPP5CALDH1A1THRBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8637684-B2	Tautomycetin and tautomycetin analog biosynthesis	WISCONSIN ALUMNI RESEARCH FOUNDATION (US)	2014-01-28	—	—	US	disclosed