Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 10/20 | 0.47 |
| ▸ | FABP2 | P12104 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445136 | 0.86 | PPARA (0.52) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL5331403 | 0.82 | MAOB (0.53) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL2560853 | 0.81 | PPARA (0.65) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL1793221 | 0.76 | KMT2A (0.49) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL14190690 | 0.76 | PPARA (0.40) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL2096397 | 0.76 | CA5A (0.41) | MAPTLMNACA5A | |
| SCHEMBL659617 | 0.76 | PPARA (0.53) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL2666313 | 0.75 | PPARA (0.41) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL3526757 | 0.74 | PPARA (0.67) | PPARAMEN1KMT2ACYP2C19CYP1A2 | |
| SCHEMBL3598533 | 0.74 | PPARA (0.52) | PPARAMEN1KMT2ACYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2689847-A1 | Methods for catalytic alkylation of nucleic acids | Universität Basel (CH) | 2014-01-29 | — | — | EP | disclosed |