Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13857762 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA | |
| SCHEMBL15075352 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA | |
| SCHEMBL14037391 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA | |
| SCHEMBL12477732 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA | |
| SCHEMBL1287234 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA | |
| SCHEMBL13021344 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA | |
| SCHEMBL14604841 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA | |
| SCHEMBL21418908 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA | |
| SCHEMBL21418911 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA | |
| SCHEMBL13941468 | 1.00 | ALDH1A1 (0.49) | ALDH1A1NPC1MAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525209-B1 | 1'-, 2'- AND 3' -MODIFIED NUCLEOSIDE DERIVATIVES FOR TREATING FLAVIVIRIDAE INFECTIONS | IDENIX PHARMACEUTICALS LLC (US) | 2017-11-15 | — | — | EP | disclosed |
| US-8637475-B1 | Modified 2′ and 3′ nucleoside prodrugs for treating flaviviridae infections | IDENIX PHARMACEUTICALS, INC. (US) | 2014-01-28 | — | — | US | disclosed |