SCHEMBL15445490

SCHEMBL15445490

CNC(=O)c1cccc(C(=O)Nc2ccc(S(=O)(=O)c3ccc(C)cc3)cc2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.65
KMT2A Q03164 6/20 0.60
MEN1 O00255 5/20 0.60
PRMT1 Q99873 2/20 0.60
HPGD P15428 1/20 0.57
PKM P14618 1/20 0.56
NPC1 O15118 4/20 0.56
RAB9A P51151 4/20 0.56
TP53 P04637 2/20 0.56
KDM4E B2RXH2 2/20 0.56
TSHR P16473 1/20 0.56
NFKB1 P19838 1/20 0.56
NFKB2 Q00653 1/20 0.56
RELA Q04206 1/20 0.56
MAPT P10636 4/20 0.55
HTT P42858 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
CYP2C9 P11712 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10199571 0.90 NPC1 (0.67) SMN1; SMN2KMT2AMEN1NPC1RAB9A
SCHEMBL12084276 0.89 NPC1 (0.67) SMN1; SMN2KMT2AMEN1PRMT1HPGD
SCHEMBL18517741 0.86 NPC1 (0.61) SMN1; SMN2KMT2AMEN1NPC1RAB9A
SCHEMBL15445492 0.85 NPC1 (0.61) SMN1; SMN2KMT2AMEN1PRMT1HPGD
SCHEMBL13967735 0.81 KMT2A (0.63) SMN1; SMN2KMT2AMEN1PRMT1HPGD
SCHEMBL7048848 0.80 PRMT1 (0.81) SMN1; SMN2KMT2AMEN1PRMT1HPGD
SCHEMBL17827157 0.79 SMN1; SMN2 (0.60) SMN1; SMN2KMT2AMEN1NPC1RAB9A
SCHEMBL19356234 0.79 SMN1; SMN2 (0.60) SMN1; SMN2KMT2AMEN1NPC1RAB9A
SCHEMBL25668858 0.79 SMN1; SMN2 (1.00) SMN1; SMN2KMT2AMEN1NPC1RAB9A
SCHEMBL8737967 0.79 KCNK3 (0.64) SMN1; SMN2KMT2AMEN1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9988493-B2 Poly(imide-amide) copolymer, article containing poly(imide-amide) copolymer, and display device including same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-06-05 US disclosed
US-20160222166-A1 POLY(IMIDE-AMIDE) COPOLYMER, ARTICLE CONTAINING POLY(IMIDE-AMIDE) COPOLYMER, AND DISPLAY DEVICE INCLUDING SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-08-04 US disclosed
US-9365694-B2 Composition including polyimide block copolymer and inorganic particles, method of preparing same, article including same, and display device including the article SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-14 US disclosed
US-20140031499-A1 COMPOSITION INCLUDING POLYIMIDE BLOCK COPOLYMER AND INORGANIC PARTICLES, METHOD OF PREPARING SAME, ARTICLE INCLUDING SAME, AND DISPLAY DEVICE INCLUDING THE ARTICLE SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-01-30 US disclosed