SCHEMBL15445709

SCHEMBL15445709

Cc1ccc(C(=O)[C@@H]2CCC(C)CO2)c(F)c1C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
TAS1R2 Q8TE23 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15446052 0.91
SCHEMBL15445730 0.91 TAS1R3 (0.32) TAS1R3TAS1R1TAS1R2CNR1CNR2
SCHEMBL15445708 0.90 HPGD (0.33) TAS1R3TAS1R1TAS1R2HPGD
SCHEMBL15446039 0.90
SCHEMBL15445711 0.85 HPGD (0.42) TAS1R3TAS1R1TAS1R2CNR1CNR2
SCHEMBL15446048 0.83
SCHEMBL15445739 0.83
SCHEMBL15446021 0.82
SCHEMBL15445712 0.82 POLB (0.33) TAS1R3TAS1R1TAS1R2HPGD
SCHEMBL15445703 0.82 TAS1R3 (0.37) TAS1R3TAS1R1TAS1R2CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140028964-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2014-01-30 US disclosed