Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | TDO2 | P48775 | 1/20 | 0.54 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404195 | 0.93 | IDO1 (0.50) | IDO1TDO2IDO2MDM2APAF1 | |
| SCHEMBL155750 | 0.85 | IDO1 (0.43) | IDO1TDO2IDO2NTRK1KDM4E | |
| SCHEMBL142563 | 0.83 | NTRK1 (0.48) | IDO1TDO2IDO2NTRK1KMT2A | |
| SCHEMBL3408954 | 0.82 | IDO1 (0.55) | IDO1TDO2IDO2APAF1NTRK1 | |
| SCHEMBL152432 | 0.82 | IDO1 (0.55) | IDO1TDO2IDO2APAF1NTRK1 | |
| SCHEMBL152297 | 0.81 | IDO1 (0.46) | IDO1TDO2IDO2APAF1NTRK1 | |
| SCHEMBL3408432 | 0.80 | IDO1 (0.46) | IDO1TDO2IDO2APAF1NTRK1 | |
| SCHEMBL153093 | 0.80 | IDO1 (0.46) | IDO1TDO2IDO2MDM2MDM4 | |
| SCHEMBL24948911 | 0.78 | IDO1 (0.46) | IDO1TDO2IDO2MDM2APAF1 | |
| SCHEMBL3406408 | 0.78 | NTRK1 (0.49) | IDO1TDO2IDO2NTRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2427431-A1 | NOVEL INDICATOR PLATFORM | Biosynth AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |
| WO-2010128120-A1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2010-11-11 | — | — | WO | disclosed |