Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL154458 | 0.80 | IDO1 (0.54) | IDO1TDO2IDO2NTRK1MEN1 | |
| SCHEMBL152432 | 0.79 | IDO1 (0.55) | IDO1TDO2IDO2NTRK1GSK3B | |
| SCHEMBL3408954 | 0.76 | IDO1 (0.55) | IDO1TDO2IDO2NTRK1GSK3B | |
| SCHEMBL152297 | 0.75 | IDO1 (0.46) | IDO1TDO2IDO2NTRK1MEN1 | |
| SCHEMBL3404195 | 0.74 | IDO1 (0.50) | IDO1TDO2IDO2NTRK1APAF1 | |
| SCHEMBL3406408 | 0.74 | NTRK1 (0.49) | IDO1TDO2IDO2NTRK1GSK3B | |
| SCHEMBL153093 | 0.72 | IDO1 (0.46) | IDO1TDO2IDO2MEN1KMT2A | |
| SCHEMBL155750 | 0.70 | IDO1 (0.43) | IDO1TDO2IDO2NTRK1GSK3B | |
| SCHEMBL28431351 | 0.67 | NTRK1 (0.54) | NTRK1GSK3BGSK3AMEN1RGS12 | |
| SCHEMBL8127015 | 0.65 | S100A4 (0.42) | IDO1TDO2IDO2APAF1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |