SCHEMBL15460202

SCHEMBL15460202

CC1(C)c2ccccc2-c2cc3c(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)cc4c5cc(-c6ccc(N(c7ccccc7)c7ccccc7)cc6)c6cc7c(cc6c5oc4c3cc21)C(C)(C)c1ccccc1-7

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460236 0.88 MAPT (0.33) MAPTPDK2
SCHEMBL26165566 0.88 ALOX5 (0.34) PDK2
SCHEMBL24586688 0.87 PRKDC (0.33) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL26165581 0.86 ALOX5 (0.33) PDK2
SCHEMBL24585672 0.86 ALOX5 (0.33) PDK2
SCHEMBL15460281 0.85 KDM4E (0.31) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL14725790 0.85 KDM4E (0.31) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL24585843 0.85 PRKDC (0.33) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL24585857 0.85 PRKDC (0.33) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL15461835 0.84 PDK2 (0.30) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed