SCHEMBL15460209

SCHEMBL15460209

c1ccc2c(c1)oc1ccc(-c3cc4c5cc(-c6ccc7oc8ccccc8c7c6)c6c(ccc7oc8ccccc8c76)c5oc4c4ccc5oc6ccccc6c5c34)cc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
ALOX5 P09917 1/20 0.40
AHR P35869 3/20 0.39
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
PLA2G10 O15496 1/20 0.36
PGR P06401 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460186 0.86 ALOX5 (0.49) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15460288 0.84 MAPT (0.41) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15460208 0.82 TNKS (0.36) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15462964 0.82 KDM4E (0.50) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15460205 0.80 CYP11B1 (0.43) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15460219 0.79 MAPT (0.52) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15460206 0.79 KDM4E (0.47) MAPTKDM4EALDH1A1HPGDNPC1
SCHEMBL28821558 0.78 MAPT (0.50) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL15945785 0.78 MAPT (0.50) MAPTMEN1KMT2AKDM4EALDH1A1
SCHEMBL19110423 0.78 ALOX5 (0.40) MAPTMEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed