SCHEMBL15460324

SCHEMBL15460324

c1ccc2c(c1)oc1ccc(-c3cc4sc5cc(-c6ccc7oc8ccccc8c7c6)c6ccccc6c5c4c4ccccc34)cc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.45
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
NPC1 O15118 2/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
RAB9A P51151 1/20 0.45
AHR P35869 2/20 0.41
HSP90AA1 P07900 1/20 0.40
HSP90AB1 P08238 1/20 0.40
ALOX5 P09917 1/20 0.39
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
PLA2G2A P14555 3/20 0.36
PLA2G4A P47712 3/20 0.36
LMNA P02545 1/20 0.35
CASP3 P42574 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460336 0.91 MAPT (0.41) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL15460320 0.88 MAPT (0.36) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL15460219 0.85 MAPT (0.52) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL15460316 0.85 MAPT (0.38) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL19076881 0.85 NPC1 (0.35) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL19077541 0.84 MEN1 (0.35) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL13408685 0.82 MAPT (0.49) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL13019758 0.82 MAPT (0.49) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL19076887 0.82 MAPT (0.35) MAPTKDM4EALDH1A1HPGDSMN1; SMN2
SCHEMBL19076923 0.82 ALOX5 (0.35) MAPTKDM4EALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed