SCHEMBL15460334

SCHEMBL15460334

c1ccc2c(c1)oc1cc3c(-c4cccc5c4sc4ccccc45)cc4sc5cc(-c6cccc7c6sc6ccccc67)c6cc7oc8ccccc8c7cc6c5c4c3cc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
PRKDC P78527 7/20 0.42
PARP14 Q460N5 1/20 0.38
PIK3CD O00329 2/20 0.38
PIK3CB P42338 2/20 0.38
BRD4 O60885 1/20 0.38
PIK3CA P42336 1/20 0.38
MTOR P42345 1/20 0.38
PIK3CG P48736 1/20 0.38
KCNH2 Q12809 1/20 0.38
BRDT Q58F21 1/20 0.38
AHR P35869 2/20 0.36
GPR3 P46089 1/20 0.34
MAOA P21397 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 3/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460250 0.93 ALOX5 (0.45) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL14725742 0.86 ALOX5 (0.44) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL16472842 0.86 ALOX5 (0.44) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL16472944 0.86 ALOX5 (0.41) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL21180622 0.85 ALOX5 (0.43) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL21180584 0.84 ALOX5 (0.43) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL16472834 0.83 ALOX5 (0.41) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL16472824 0.82 ALOX5 (0.40) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL15460307 0.81 ALOX5 (0.53) ALOX5PRKDCPARP14PIK3CDPIK3CB
SCHEMBL15460330 0.80 AHR (0.38) PRKDCAHRMAOAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed