SCHEMBL15460741

SCHEMBL15460741

CCCc1ccc(C(F)(F)Oc2cc(F)c(C(F)(F)Oc3cc(F)c(OC=C(F)F)c(F)c3)c(F)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460642 0.92 MAOB (0.32) THRB
SCHEMBL15461297 0.92 MAOB (0.32) THRB
SCHEMBL15461301 0.90 RARB (0.32) THRB
SCHEMBL15460639 0.90 RARB (0.32) THRB
SCHEMBL15460742 0.88
SCHEMBL15461321 0.88 RARB (0.31)
SCHEMBL15461328 0.87 RARB (0.30)
SCHEMBL15461305 0.87 RARB (0.30)
SCHEMBL15461310 0.86 PPARG (0.33) THRB
SCHEMBL15460636 0.86 S1PR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9273245-B2 Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-03-01 US disclosed
US-9273245-B2 Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-03-01 US disclosed
US-20140034876-A1 COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-02-06 US disclosed
US-20140034876-A1 COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-02-06 US disclosed