SCHEMBL15460642

SCHEMBL15460642

CCCc1ccc(-c2ccc(C(F)(F)Oc3cc(F)c(OC=C(F)F)c(F)c3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.32
RARB P10826 2/20 0.31
RARA P10276 1/20 0.31
RARG P13631 1/20 0.31
MCL1 Q07820 1/20 0.31
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15461297 1.00 MAOB (0.32) MAOBRARBRARARARGMCL1
SCHEMBL15461321 0.95 RARB (0.31) RARBRARARARG
SCHEMBL15461310 0.94 PPARG (0.33) MAOBRARBRARARARGMCL1
SCHEMBL15461299 0.93 S1PR1 (0.35) RARBRARARARG
SCHEMBL15461296 0.93 RARB (0.41) RARBRARARARGTHRB
SCHEMBL15460657 0.93 RARB (0.41) RARBRARARARGTHRB
SCHEMBL15460741 0.92 THRB (0.32) THRB
SCHEMBL15460641 0.91 S1PR1 (0.35) RARB
SCHEMBL15460639 0.89 RARB (0.32) RARBRARARARGMCL1THRB
SCHEMBL15461301 0.89 RARB (0.32) RARBRARARARGMCL1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9273245-B2 Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-03-01 US disclosed
US-9273245-B2 Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-03-01 US disclosed
US-20140034876-A1 COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-02-06 US disclosed
US-20140034876-A1 COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-02-06 US disclosed