SCHEMBL15460799

SCHEMBL15460799

CCCCCc1ccc(-c2ccc(-c3cc(F)c(C(F)(F)Oc4cc(F)c(OC=C(F)F)c(F)c4)c(F)c3)c(F)c2)c(F)c1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.39
RARA P10276 1/20 0.34
RARG P13631 1/20 0.34
S1PR1 P21453 3/20 0.33
S1PR3 Q99500 2/20 0.33
FAAH O00519 1/20 0.33
PTGS2 P35354 1/20 0.33
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460796 0.94 RARB (0.41) RARBRARARARGS1PR1S1PR3
SCHEMBL15460800 0.94 ALOX5 (0.31) RARBS1PR1S1PR3
SCHEMBL15460821 0.93 S1PR1 (0.34) RARBS1PR1S1PR3FAAHPTGS2
SCHEMBL15461325 0.92 RARB (0.40) RARBRARARARGS1PR1S1PR3
SCHEMBL15461039 0.91 RARB (0.38) RARBRARARARGS1PR1S1PR3
SCHEMBL15461033 0.90
SCHEMBL15460667 0.90 RARB (0.40) RARBRARARARGS1PR1S1PR3
SCHEMBL15460781 0.89 RARB (0.38) RARBRARARARGS1PR1S1PR3
SCHEMBL15460795 0.89 RARB (0.43) RARBRARARARGFAAHTHRB
SCHEMBL15461307 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9273245-B2 Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-03-01 US disclosed
US-9273245-B2 Compound having 2,2-difluorovinyloxy group or 1,2,2-trifluorovinyloxy group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2016-03-01 US disclosed
US-20140034876-A1 COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-02-06 US disclosed
US-20140034876-A1 COMPOUND HAVING 2,2-DIFLUOROVINYLOXY GROUP OR 1,2,2-TRIFLUOROVINYLOXY GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-02-06 US disclosed