SCHEMBL15463534

SCHEMBL15463534

CC(NC(=O)c1cc(Cl)cnc1COc1ccc(F)cc1)c1ccc(C(=O)O)cc1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 20/20 0.75
PTGER2 P43116 6/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3983551 1.00 PTGER4 (0.75) PTGER4PTGER2
SCHEMBL691834 0.93 PTGER4 (0.73) PTGER4PTGER2
SCHEMBL15463569 0.93 PTGER4 (0.73) PTGER4PTGER2
SCHEMBL3981573 0.91 PTGER4 (0.62) PTGER4PTGER2
SCHEMBL3983167 0.91 PTGER4 (0.62) PTGER4PTGER2
SCHEMBL692562 0.90 PTGER4 (0.64) PTGER4PTGER2
SCHEMBL22076506 0.90 PTGER4 (0.64) PTGER4PTGER2
SCHEMBL27653394 0.90 PTGER4 (0.76) PTGER4PTGER2
SCHEMBL3981739 0.90 PTGER4 (0.76) PTGER4PTGER2
SCHEMBL27661920 0.88 PTGER4 (0.58) PTGER4PTGER2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1756042-B1 SUBSTITUTED METHYL ARYL OR HETEROARYL AMIDE COMPOUNDS RAQUALIA PHARMA INC (JP) 2014-02-12 EP disclosed
CN-1950333-A Substituted methyl aryl or heteroaryl amide compounds PFIZER (US) 2007-04-18 CN disclosed