Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.73 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.64 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL691834 | 1.00 | PTGER4 (0.73) | PTGER4PTGER2RXRARXRB | |
| SCHEMBL3983551 | 0.93 | PTGER4 (0.75) | PTGER4PTGER2 | |
| SCHEMBL15463534 | 0.93 | PTGER4 (0.75) | PTGER4PTGER2 | |
| SCHEMBL22076506 | 0.91 | PTGER4 (0.64) | PTGER4PTGER2 | |
| SCHEMBL692562 | 0.91 | PTGER4 (0.64) | PTGER4PTGER2 | |
| SCHEMBL3978649 | 0.91 | PTGER4 (0.61) | PTGER4PTGER2 | |
| SCHEMBL690945 | 0.89 | PTGER4 (0.75) | PTGER4PTGER2RXRARXRB | |
| SCHEMBL5502232 | 0.89 | PTGER4 (0.75) | PTGER4PTGER2RXRARXRB | |
| SCHEMBL27681503 | 0.87 | PTGER4 (0.56) | PTGER4PTGER2RXRARXRB | |
| SCHEMBL3981739 | 0.87 | PTGER4 (0.76) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102421429-A | Selective EP4 receptor antagonist for cancer therapy | RAQUALIA PHARMA INC | 2012-04-18 | — | — | CN | claimed |
| CN-1950333-A | Substituted methyl aryl or heteroaryl amide compounds | PFIZER (US) | 2007-04-18 | — | — | CN | claimed |
| EP-1756042-B1 | SUBSTITUTED METHYL ARYL OR HETEROARYL AMIDE COMPOUNDS | RAQUALIA PHARMA INC (JP) | 2014-02-12 | — | — | EP | disclosed |
| CN-102770159-A | Use of EP-4 receptor antagonists for the treatment of IL-23 mediated diseases | RAQUALIA PHARMA INC | 2012-11-07 | — | — | CN | disclosed |
| CN-102421429-A | Selective EP4 receptor antagonist for cancer therapy | RAQUALIA PHARMA INC | 2012-04-18 | — | — | CN | disclosed |
| CN-1950333-A | Substituted methyl aryl or heteroaryl amide compounds | PFIZER (US) | 2007-04-18 | — | — | CN | disclosed |
| CN-1946391-A | Combinations comprising alpha-2-delta ligands | PFIZER PROD INC (US) | 2007-04-11 | — | — | CN | disclosed |