Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.64 |
| ▸ | GABRD | O14764 | 1/20 | 0.64 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.64 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.64 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.64 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.64 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.64 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.64 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.64 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.64 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.64 |
| ▸ | GABRE | P78334 | 1/20 | 0.64 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.64 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.64 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.64 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL28175311 | 0.84 | MEN1 (0.58) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL22524482 | 0.83 | TRPA1 (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19936078 | 0.80 | SRD5A2 (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29851592 | 0.80 | SRD5A2 (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28171876 | 0.79 | TRPA1 (0.60) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6536547 | 0.78 | SRD5A1 (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19936045 | 0.78 | SRD5A2 (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19936049 | 0.78 | SRD5A2 (0.55) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13236269 | 0.78 | MAPT (0.70) | SRD5A2MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28171211 | 0.78 | SRD5A2 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583948-A | Novel crystalline forms of POL1 inhibitor | 皮梅拉股份有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-110709400-A | Novel crystalline forms of POL1 inhibitor | 皮梅拉股份有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-106459068-B | Novel compositions, uses and processes for their preparation | 皮梅拉股份有限公司 | 2019-01-22 | — | — | CN | disclosed |
| CN-106995443-A | New compositions, purposes and the method for preparing them | 皮梅拉股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-106459068-A | Novel compositions, uses and processes for their preparation | 皮梅拉股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| EP-1991526-B1 | Tetracyclic indole derivatives as in vivo imaging agents and having peripheralbenzodiazepine receptor affinity (PBR) | HAMMERSMITH IMANET LTD (GB) | 2014-02-12 | — | — | EP | disclosed |