Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 17/20 | 0.58 |
| ▸ | PTGER2 | P43116 | 6/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.54 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692225 | 1.00 | PTGER4 (0.58) | PTGER4PTGER2NR4A2PHGDH | |
| SCHEMBL692553 | 0.95 | PTGER4 (0.64) | PTGER4PTGER2NR4A2PHGDH | |
| SCHEMBL26914668 | 0.91 | PTGER4 (0.71) | PTGER4PTGER2NR4A2 | |
| SCHEMBL692242 | 0.91 | PTGER4 (0.71) | PTGER4PTGER2NR4A2 | |
| SCHEMBL3980893 | 0.91 | PTGER4 (0.48) | PTGER4PTGER2NR4A2 | |
| SCHEMBL692175 | 0.88 | PTGER4 (0.61) | PTGER4PTGER2NR4A2 | |
| SCHEMBL22076482 | 0.88 | PTGER4 (0.61) | PTGER4PTGER2NR4A2 | |
| SCHEMBL692172 | 0.88 | PTGER4 (0.70) | PTGER4PTGER2NR4A2 | |
| SCHEMBL691363 | 0.88 | PTGER4 (0.63) | PTGER4PTGER2NR4A2 | |
| SCHEMBL5188816 | 0.88 | PTGER4 (0.70) | PTGER4PTGER2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756042-B1 | SUBSTITUTED METHYL ARYL OR HETEROARYL AMIDE COMPOUNDS | RAQUALIA PHARMA INC (JP) | 2014-02-12 | — | — | EP | disclosed |