Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42138 | 0.91 | TDP1 (0.64) | TDP1CYP3A4ALOX15TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL7930921 | 0.89 | TDP1 (0.61) | TDP1CYP3A4ALOX15TSHRHSD17B10 | |
| Water SCHEMBL11613455 | 0.89 | TDP1 (0.61) | TDP1CYP3A4ALOX15TSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL6328090 | 0.86 | TDP1 (0.58) | TDP1CYP3A4ALOX15TSHRHSD17B10 | |
| Sulfuric Acid SCHEMBL10588282 | 0.81 | ALDH1A1 (0.55) | TDP1CYP3A4ALOX15TSHRHSD17B10 | |
| Lactic Acid SCHEMBL11230703 | 0.79 | TDP1 (0.50) | TDP1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL17104285 | 0.77 | TDP1 (0.58) | TDP1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL28172850 | 0.77 | TDP1 (0.58) | TDP1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL14515472 | 0.77 | TDP1 (0.58) | TDP1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL4167974 | 0.77 | TDP1 (0.46) | TDP1CYP3A4ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293711-B2 | Organic semiconductor formulations | POLYERA CORPORATION (US) | 2016-03-22 | — | — | US | claimed |
| US-20140042369-A1 | Organic Semiconductor Formulations | USINVEST LLC | 2014-02-13 | — | — | US | claimed |
| US-10043978-B2 | Organic semiconductor formulations | FLEXTERRA, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| US-20170012208-A1 | ORGANIC SEMICONDUCTOR FORMULATIONS | USINVEST LLC | 2017-01-12 | — | — | US | disclosed |
| US-9293711-B2 | Organic semiconductor formulations | POLYERA CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20140042369-A1 | Organic Semiconductor Formulations | USINVEST LLC | 2014-02-13 | — | — | US | disclosed |