SCHEMBL15466643

SCHEMBL15466643

C=CC1CC2CC1CC2c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.41
HTR2C P28335 8/20 0.41
MAOA P21397 7/20 0.41
KDM1A O60341 5/20 0.41
CYP2C19 P33261 4/20 0.41
CYP2B6 P20813 3/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C9 P11712 2/20 0.41
LMNA P02545 2/20 0.41
TAAR1 Q96RJ0 2/20 0.41
CYP3A4 P08684 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CYP2A6 P11509 1/20 0.41
SLC6A2 P23975 1/20 0.41
ADRA1A P35348 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KCNH2 Q12809 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL899999 0.81 MAOB (0.41) MAOBHTR2CMAOAKDM1ACYP2C19
SCHEMBL3189756 0.78 MAOB (0.48) MAOBHTR2CMAOAKDM1ACYP2C19
SCHEMBL3189760 0.78 MAOB (0.48) MAOBHTR2CMAOAKDM1ACYP2C19
SCHEMBL21035178 0.75 HDAC4 (0.38) MAOBHTR2CMAOAKDM1ACYP2C19
SCHEMBL22495822 0.75 HDAC4 (0.38) MAOBHTR2CMAOAKDM1ACYP2C19
SCHEMBL1697579 0.72 MAOB (0.41) MAOBHTR2CMAOAKDM1ACYP2C19
SCHEMBL9461901 0.72 MAOB (0.42) MAOBHTR2CMAOAKDM1ACYP2C19
SCHEMBL21035177 0.70 SLC6A3 (0.41) KDM1ASLC6A3
SCHEMBL22495865 0.70 SLC6A3 (0.41) KDM1ASLC6A3
SCHEMBL27447081 0.69 MEN1 (0.46) MAOBHTR2CMAOAKDM1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2019-03-12 US disclosed
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2016-12-22 US disclosed
US-9468890-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation PROMERUS, LLC (US) 2016-10-18 US disclosed
EP-2870129-B1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION SUMITOMO BAKELITE CO (JP) 2016-04-06 EP disclosed
EP-2870129-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION Promerus, LLC (US) 2015-05-13 EP disclosed
US-20140042090-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 US disclosed
WO-2014025735-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION PROMERUS, LLC (US) 2014-02-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160369026-A1 CYCLOALKYLNORBORNENE MONOMERS, POLYMERS DERIVED THEREFROM AND THEIR USE IN PERVAPORATION NOTUM, AGPS, WEE1 MAOB 4267/4885HTR2C 4637/4885MAOA 4162/4885
US-10227433-B2 Cycloalkylnorbornene monomers, polymers derived therefrom and their use in pervaporation NOTUM, AGPS, WEE1 MAOB 4267/4885HTR2C 4637/4885MAOA 4162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.