⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL284799 | 1.00 | — | — | |
| Propane SCHEMBL8421282 | 1.00 | — | — | |
| Propane SCHEMBL187937 | 1.00 | — | — | |
| Propane SCHEMBL9016580 | 1.00 | TSHR (0.38) | — | |
| Propane SCHEMBL30443431 | 0.91 | ALDH1A1 (0.36) | — | |
| Propane SCHEMBL19178222 | 0.91 | — | — | |
| Propane SCHEMBL1248581 | 0.91 | — | — | |
| Propane SCHEMBL19180052 | 0.91 | — | — | |
| Propane SCHEMBL29119454 | 0.91 | — | — | |
| Propane SCHEMBL5595730 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2703411-B1 | NANOPARTICLES CONTAINING PH-RESPONSIVE PEPTIDE | TAIHO PHARMACEUTICAL CO LTD (JP) | 2017-10-11 | — | — | EP | disclosed |
| EP-2910564-B1 | WEAKLY ACIDIC PH-RESPONSIVE PEPTIDE AND LIPOSOME CONTAINING SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2017-03-22 | — | — | EP | disclosed |
| US-9526791-B2 | Weakly acidic pH-responsive peptide and liposome containing same | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-12-27 | — | — | US | disclosed |
| US-9186389-B2 | Nanoparticles containing pH-responsive peptide | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150250893-A1 | WEAKLY ACIDIC pH-RESPONSIVE PEPTIDE AND LIPOSOME CONTAINING SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-10 | — | — | US | disclosed |
| EP-2910564-A1 | WEAKLY ACIDIC pH-RESPONSIVE PEPTIDE AND LIPOSOME CONTAINING SAME | Taiho Pharmaceutical Co., Ltd. (JP) | 2015-08-26 | — | — | EP | disclosed |
| EP-2703411-A1 | NANOPARTICLES CONTAINING pH-RESPONSIVE PEPTIDE | Taiho Pharmaceutical Co., Ltd. (JP) | 2014-03-05 | — | — | EP | disclosed |
| US-20140044778-A1 | NANOPARTICLES CONTAINING pH-RESPONSIVE PEPTIDE | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |