Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 6/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20898696 | 1.00 | POLB (0.43) | POLBSLC6A4CHRM2ADRA2BSLC6A2 | |
| SCHEMBL20898695 | 1.00 | POLB (0.43) | POLBSLC6A4CHRM2ADRA2BSLC6A2 | |
| SCHEMBL20898694 | 1.00 | POLB (0.43) | POLBSLC6A4CHRM2ADRA2BSLC6A2 | |
| Cadaverine Tartrate SCHEMBL20898278 | 0.86 | POLB (0.45) | POLBSLC6A4CHRM2ADRA2BSLC6A2 | |
| Cadaverine Tartrate SCHEMBL8638485 | 0.86 | POLB (0.45) | POLBSLC6A4CHRM2ADRA2BSLC6A2 | |
| Cadaverine Tartrate SCHEMBL20898382 | 0.86 | POLB (0.45) | POLBSLC6A4CHRM2ADRA2BSLC6A2 | |
| Cadaverine Tartrate SCHEMBL20898277 | 0.86 | POLB (0.45) | POLBSLC6A4CHRM2ADRA2BSLC6A2 | |
| SCHEMBL1499960 | 0.86 | SLC6A4 (0.49) | POLBSLC6A4CHRM2ADRA2BSLC6A2 | |
| SCHEMBL2805296 | 0.86 | SLC6A4 (0.49) | POLBSLC6A4CHRM2ADRA2BSLC6A2 | |
| SCHEMBL2803588 | 0.86 | SLC6A4 (0.49) | POLBSLC6A4CHRM2ADRA2BSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140046068-A1 | METHOD OF SYNTHESIZING BEPOTASTINE OR BENZENESULFONIC ACID SALT THEREOF AND INTERMEDIATES USED THEREIN | EVERLIGHT USA, INC. (US) | 2014-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140046068-A1 | METHOD OF SYNTHESIZING BEPOTASTINE OR BENZENESULFONIC ACID SALT THEREOF AND INTERMEDIATES USED THEREIN | CYP7A1, HRH3, HRH2 | POLB 1678/4885SLC6A4 1680/4885CHRM2 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.