Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.42 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.42 |
| ▸ | HRH1 known ✓ | P35367 | 1/20 | 0.42 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 8/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL20898277 | 1.00 | POLB (0.45) | POLBSLC6A4LMNACHRM2ADRA2B | |
| Cadaverine Tartrate SCHEMBL20898278 | 1.00 | POLB (0.45) | POLBSLC6A4LMNACHRM2ADRA2B | |
| Cadaverine Tartrate SCHEMBL20898382 | 1.00 | POLB (0.45) | POLBSLC6A4LMNACHRM2ADRA2B | |
| SCHEMBL1499960 | 0.91 | SLC6A4 (0.49) | POLBSLC6A4LMNACHRM2ADRA2B | |
| SCHEMBL2803588 | 0.91 | SLC6A4 (0.49) | POLBSLC6A4LMNACHRM2ADRA2B | |
| SCHEMBL2805296 | 0.91 | SLC6A4 (0.49) | POLBSLC6A4LMNACHRM2ADRA2B | |
| SCHEMBL20898694 | 0.86 | POLB (0.43) | POLBSLC6A4LMNACHRM2ADRA2B | |
| SCHEMBL15467772 | 0.86 | POLB (0.43) | POLBSLC6A4LMNACHRM2ADRA2B | |
| SCHEMBL20898696 | 0.86 | POLB (0.43) | POLBSLC6A4LMNACHRM2ADRA2B | |
| SCHEMBL20898695 | 0.86 | POLB (0.43) | POLBSLC6A4LMNACHRM2ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10182635-A | — | — | None | — | — | JP | disclosed |
| JP-H10182635-A | OPTICALLY ACTIVE PIPERIDINE DERIVATIVE AND ITS PRODUCTION | UBE IND LTD | 1998-07-07 | — | — | JP | disclosed |