Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5974836 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL6377053 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL4263976 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL6377056 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL5974842 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL8390475 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL7215485 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL7215482 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL22758821 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 | |
| SCHEMBL4263978 | 0.96 | PTPN1 (0.47) | TSHRLMNAKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648188-B2 | Preparation of 2-chloro-9-(2′-deoxy-2′-fluoro-β-D-arabinofuranosyl)-adenine | SCINOPHARM TAIWAN, LTD. (TW) | 2014-02-11 | — | — | US | disclosed |