SCHEMBL15468449

SCHEMBL15468449

COCCOC(=O)[C@@H](CC(C)(C)C)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.35
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10066324 1.00 TSHR (0.35) TSHRCA12CA1CA2CA9
SCHEMBL21148174 0.95 TSHR (0.33) TSHRCA12CA1CA2CA9
SCHEMBL21148406 0.95 TSHR (0.33) TSHRCA12CA1CA2CA9
SCHEMBL21148403 0.95 TSHR (0.33) TSHRCA12CA1CA2CA9
SCHEMBL21148169 0.95 TSHR (0.33) TSHRCA12CA1CA2CA9
SCHEMBL24400257 0.95 TSHR (0.33) TSHRCA12CA1CA2CA9
SCHEMBL21556176 0.95 TSHR (0.33) TSHRCA12CA1CA2CA9
SCHEMBL20107525 0.89 ALDH1A1 (0.37) TSHR
SCHEMBL20107659 0.89 ALDH1A1 (0.33) TSHR
SCHEMBL20107821 0.87 ALDH1A1 (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2096150-B1 Aqueous colorant dispersion, production method of aqueous colorant dispersion, and aqueous ink for inkjet recording FUJIFILM CORP (JP) 2014-02-12 EP disclosed