Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30274800 | 0.80 | PTPN1 (0.41) | BCHETSHRABCB1 | |
| SCHEMBL10126419 | 0.75 | TSHR (0.35) | TSHR | |
| SCHEMBL10126288 | 0.75 | TSHR (0.37) | CA1CA2CA9TSHR | |
| SCHEMBL16386068 | 0.75 | TSHR (0.37) | CA1CA2CA9TSHR | |
| SCHEMBL31645107 | 0.74 | SMYD2 (0.33) | BCHEPOLBSMYD2CYP3A4HTT | |
| SCHEMBL8462236 | 0.72 | SLC18A3 (0.43) | BCHETSHRSLC18A3 | |
| SCHEMBL872255 | 0.72 | TSHR (0.39) | POLBTSHR | |
| SCHEMBL18512832 | 0.72 | LMNA (0.39) | SMYD2CYP3A4TSHR | |
| SCHEMBL13433828 | 0.72 | SMYD2 (0.32) | SMYD2CYP3A4HTTSMN1; SMN2ABCB1 | |
| SCHEMBL610200 | 0.72 | SMYD2 (0.33) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562971-B1 | POLYCYCLIC SUGAR SURROGATE-CONTAINING OLIGOMERIC COMPOUNDS AND COMPOSITIONS FOR USE IN GENE MODULATION | ISIS PHARMACEUTICALS INC (US) | 2014-02-12 | — | — | EP | disclosed |