Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1322724 | 0.94 | PPARA (0.35) | PPARAHPGDMAPTNPY1RNPY2R | |
| SCHEMBL30025507 | 0.84 | CYP11B1 (0.33) | PPARAMAPT | |
| SCHEMBL2949533 | 0.83 | ALDH1A1 (0.39) | PPARAHPGDMAPTNPY1RNPY2R | |
| SCHEMBL13017182 | 0.82 | MAOB (0.41) | PPARAHPGDMAPTSMN1; SMN2BRD4 | |
| SCHEMBL26297255 | 0.82 | MAPT (0.37) | PPARAHPGDMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL2303739 | 0.80 | ALDH1A1 (0.37) | PPARASMN1; SMN2BRD4MCHR1ALDH1A1 | |
| SCHEMBL30025345 | 0.80 | PPARA (0.35) | PPARAHPGDSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL13784389 | 0.78 | HPGD (0.36) | PPARAHPGDMAPTNPY1RNPY2R | |
| SCHEMBL3422458 | 0.78 | ALDH1A1 (0.37) | PPARAHPGDMAPTNPY1RNPY2R | |
| SCHEMBL30025944 | 0.77 | BRS3 (0.34) | PPARAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2223926-B1 | PYRIDINE DERIVATIVE SUBSTITUTED WITH HETEROCYCLE AND PHOSPHONOXYMETHYL GROUP AND ANTIFUNGAL AGENT CONTAINING THE SAME | EISAI R&D MAN CO LTD (JP) | 2014-02-12 | — | — | EP | disclosed |