SCHEMBL15468575

SCHEMBL15468575

Bc1ccc(-c2cccc(-c3cccc(-c4ccccc4)c3)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.50
ESR1 P03372 2/20 0.50
KMT2A Q03164 2/20 0.50
MAOA P21397 1/20 0.48
ALDH1A1 P00352 3/20 0.47
KMO O15229 1/20 0.46
ALOX5 P09917 1/20 0.46
ACMSD Q8TDX5 1/20 0.45
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 1/20 0.44
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
ABL1 P00519 1/20 0.43
ABCB1 P08183 1/20 0.43
BCR P11274 1/20 0.43
MGLL Q99685 1/20 0.43
TAAR1 Q96RJ0 2/20 0.42
APP P05067 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HSD17B10 Q99714 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14653447 1.00 MEN1 (0.50) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL19558293 0.92 ALDH1A1 (0.50) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL320180 0.89 ALDH1A1 (0.60) ALDH1A1ALOX5CYP3A4MGLLTAAR1
SCHEMBL14067584 0.89 ALDH1A1 (0.60) ALDH1A1ALOX5CYP3A4MGLLTAAR1
SCHEMBL17209157 0.89 ALDH1A1 (0.60) ALDH1A1ALOX5CYP3A4MGLLTAAR1
SCHEMBL18371214 0.87 MEN1 (0.48) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL18371221 0.87 MEN1 (0.48) MEN1ESR1KMT2AMAOAALDH1A1
Water SCHEMBL27704708 0.86 ALDH1A1 (0.56) ALDH1A1ALOX5CYP3A4MGLLTAAR1
SCHEMBL31254135 0.86 ALDH1A1 (0.64) MEN1ESR1KMT2AMAOAALDH1A1
SCHEMBL29792069 0.86 ALDH1A1 (0.64) MEN1ESR1KMT2AMAOAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2695882-B1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL, COMPOSITION CONTAINING SAID COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE MITSUBISHI CHEM CORP (JP) 2017-03-01 EP disclosed
EP-2695882-A1 ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL, COMPOSITION CONTAINING SAID COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE Mitsubishi Chemical Corporation (JP) 2014-02-12 EP disclosed