Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17722990 | 0.89 | P2RX7 (0.42) | P2RX7NISCHNOS2GP6SLC5A2 | |
| SCHEMBL17851200 | 0.88 | P2RX7 (0.40) | P2RX7NISCHNOS2GP6SLC5A2 | |
| SCHEMBL18561425 | 0.86 | P2RX7 (0.39) | P2RX7NISCHNOS2GP6SLC5A2 | |
| SCHEMBL17297458 | 0.84 | NISCH (0.39) | P2RX7NISCHNOS2GP6SLC5A2 | |
| SCHEMBL18560838 | 0.83 | NISCH (0.38) | P2RX7NISCHNOS2GP6SLC5A2 | |
| SCHEMBL18562519 | 0.83 | NISCH (0.38) | P2RX7NISCHNOS2GP6SLC5A2 | |
| SCHEMBL15275975 | 0.83 | NISCH (0.38) | P2RX7NISCHNOS2GP6SLC5A2 | |
| SCHEMBL18561432 | 0.82 | P2RX7 (0.38) | P2RX7NISCHNOS2GP6SLC5A2 | |
| SCHEMBL19007621 | 0.81 | P2RX7 (0.43) | P2RX7NISCHNOS2GP6SLC5A2 | |
| SCHEMBL15593069 | 0.81 | P2RX7 (0.60) | P2RX7NISCHNOS2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2695882-A1 | ORGANIC COMPOUND, CHARGE TRANSPORT MATERIAL, COMPOSITION CONTAINING SAID COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE | Mitsubishi Chemical Corporation (JP) | 2014-02-12 | — | — | EP | disclosed |