Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 2/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.46 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1969430 | 1.00 | RORC (0.51) | RORCMC4RDPP4MEN1KMT2A | |
| SCHEMBL1972532 | 1.00 | RORC (0.51) | RORCMC4RDPP4MEN1KMT2A | |
| SCHEMBL12513593 | 0.89 | STS (0.50) | RORCMC4RMEN1KMT2APDE4B | |
| SCHEMBL12435415 | 0.89 | STS (0.50) | RORCMC4RMEN1KMT2APDE4B | |
| SCHEMBL528081 | 0.89 | STS (0.50) | MC4RMEN1KMT2APDE4BSTS | |
| SCHEMBL15197029 | 0.89 | STS (0.50) | MC4RMEN1KMT2APDE4BSTS | |
| SCHEMBL12513594 | 0.87 | RORC (0.54) | RORCMEN1KMT2APDE4BNAMPT | |
| SCHEMBL1971296 | 0.87 | RORC (0.54) | RORCMEN1KMT2APDE4BNAMPT | |
| SCHEMBL1968859 | 0.87 | RORC (0.54) | RORCMEN1KMT2APDE4BNAMPT | |
| SCHEMBL528565 | 0.87 | RORC (0.54) | RORCMEN1KMT2APDE4BNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336105-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE OF SAME | TAKEDA PHARMACEUTICAL (JP) | 2014-02-12 | — | — | EP | disclosed |