Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | ASPH | Q12797 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.39 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | BCL2L10 | Q9HD36 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 7/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.38 |
| ▸ | FLT3 | P36888 | 4/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5007929 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL5007902 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL5007931 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL5007903 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL4998204 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL4998209 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL14008562 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL4043315 | 0.88 | BCL2L1 (0.45) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL14008571 | 0.88 | BCL2L1 (0.45) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL4043318 | 0.88 | BCL2L1 (0.45) | BCL2L1ASPHBCL2ADORA1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836165-B1 | DIPYRROLE COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING CANCER OR VIRAL DISEASES | GEMIN X PHARMACEUTICALS CANADA INC (CA) | 2014-02-12 | — | — | EP | disclosed |