Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.45 |
| ▸ | ASPH | Q12797 | 2/20 | 0.45 |
| ▸ | BCL2 | P10415 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.45 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.45 |
| ▸ | BAD | Q92934 | 1/20 | 0.45 |
| ▸ | BCL2L10 | Q9HD36 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 7/20 | 0.44 |
| ▸ | RET | P07949 | 6/20 | 0.37 |
| ▸ | FLT3 | P36888 | 3/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | FLT1 | P17948 | 2/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | FLT4 | P35916 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4043315 | 1.00 | BCL2L1 (0.45) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL14008571 | 1.00 | BCL2L1 (0.45) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL15468683 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL4998204 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL5007929 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL14008562 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL5007931 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL5007903 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL4998209 | 0.88 | BCL2L1 (0.39) | BCL2L1ASPHBCL2ADORA1MCL1 | |
| SCHEMBL4053033 | 0.86 | BCL2L1 (0.38) | BCL2L1ASPHBCL2ADORA1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836165-B1 | DIPYRROLE COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING CANCER OR VIRAL DISEASES | GEMIN X PHARMACEUTICALS CANADA INC (CA) | 2014-02-12 | — | — | EP | claimed |
| US-8420693-B2 | Prevent replication or infection from virus; antiproliferative agent; screening analysis | GEMIN X PHARMACEUTICALS CANADA INC. (CA) | 2013-04-16 | — | — | US | claimed |
| EP-1836165-A4 | DIPYRROLE COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING CANCER OR VIRAL DISEASES | GEMIN X PHARMACEUTICALS CANADA (CA) | 2009-07-08 | — | — | EP | claimed |
| US-20080280896-A1 | Dipyrrole Compounds, Compositions, and Methods For Treating Cancer or Viral Diseases | GEMIN X BIOTECHNOLOGIES INC. (CA) | 2008-11-13 | — | — | US | claimed |
| EP-1836165-A1 | DIPYRROLE COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING CANCER OR VIRAL DISEASES | Gemin X Biotechnologies Inc. (CA) | 2007-09-26 | — | — | EP | claimed |
| WO-2006069441-A1 | DIPYRROLE COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING CANCER OR VIRAL DISEASES | GEMIN X BIOTECHNOLOGIES INC. (CA) | 2006-07-06 | — | — | WO | claimed |
| EP-1836165-B1 | DIPYRROLE COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATING CANCER OR VIRAL DISEASES | GEMIN X PHARMACEUTICALS CANADA INC (CA) | 2014-02-12 | — | — | EP | disclosed |
| US-8420693-B2 | Prevent replication or infection from virus; antiproliferative agent; screening analysis | GEMIN X PHARMACEUTICALS CANADA INC. (CA) | 2013-04-16 | — | — | US | disclosed |
| US-20080280896-A1 | Dipyrrole Compounds, Compositions, and Methods For Treating Cancer or Viral Diseases | GEMIN X BIOTECHNOLOGIES INC. (CA) | 2008-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280896-A1 | Dipyrrole Compounds, Compositions, and Methods For Treating Cancer or Viral Diseases | ZC3HAV1, DPEP1, ING2 | BCL2L1 1867/4885ASPH 507/4885BCL2 1400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.