Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.54 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.54 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.54 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.54 |
| ▸ | TGM2 | P21980 | 1/20 | 0.53 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 3/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.49 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.49 |
| ▸ | HINT1 | P49773 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1577230 | 1.00 | NT5E (0.57) | NT5EPOLBIMPDH2TAS1R3TAS1R1 | |
| SCHEMBL12939473 | 1.00 | NT5E (0.57) | NT5EPOLBIMPDH2TAS1R3TAS1R1 | |
| SCHEMBL10819909 | 1.00 | NT5E (0.57) | NT5EPOLBIMPDH2TAS1R3TAS1R1 | |
| SCHEMBL12194800 | 1.00 | NT5E (0.57) | NT5EPOLBIMPDH2TAS1R3TAS1R1 | |
| SCHEMBL18740412 | 0.96 | NT5E (0.53) | NT5EPOLBIMPDH2TAS1R3TAS1R1 | |
| SCHEMBL723267 | 0.94 | NT5E (0.56) | NT5EPOLBIMPDH2TAS1R3TAS1R1 | |
| SCHEMBL1576874 | 0.93 | TGM2 (0.59) | NT5EPOLBIMPDH2TAS1R3TAS1R1 | |
| SCHEMBL13522449 | 0.93 | TGM2 (0.59) | NT5EPOLBIMPDH2TAS1R3TAS1R1 | |
| SCHEMBL10819892 | 0.93 | TGM2 (0.59) | NT5EPOLBIMPDH2TAS1R3TAS1R1 | |
| Inx-09114 SCHEMBL23319265 | 0.92 | P2RY2 (0.60) | NT5EPOLBIMPDH2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066793-A1 | MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| EP-2307434-B1 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF VIRAL INFECTIONS | IDENIX PHARMACEUTICALS INC (US) | 2014-02-12 | — | — | EP | disclosed |