SCHEMBL15469131

SCHEMBL15469131

CN1c2ccccc2C=Cc2cc(C(C)(C)C)ccc21

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1H3 Q13133 1/20 0.46
P2RX4 Q99571 4/20 0.38
MAPT P10636 4/20 0.37
KMT2A Q03164 4/20 0.37
MEN1 O00255 3/20 0.37
LMNA P02545 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
THRB P10828 1/20 0.37
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
ALDH1A1 P00352 2/20 0.36
PLA2G1B P04054 1/20 0.36
NFKB1 P19838 1/20 0.36
CASP3 P42574 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4996062 0.80 NR1H3 (0.47) NR1H3MAPTKMT2AMEN1NPC1
SCHEMBL2607158 0.79 MAPT (0.49) P2RX4MAPTKMT2AMEN1LMNA
SCHEMBL19885348 0.77 MAPT (0.44) P2RX4MAPTKMT2AMEN1LMNA
SCHEMBL10133839 0.75 NR1H3 (0.59) NR1H3MAPTLMNANPC1RAB9A
SCHEMBL10133841 0.74 NR1H3 (0.62) NR1H3LMNANPC1RAB9AALDH1A1
SCHEMBL23713627 0.73 NR1H3 (0.44) NR1H3MAPTKMT2AMEN1LMNA
SCHEMBL12793382 0.73 MAPT (0.40) P2RX4MAPTKMT2AMEN1LMNA
SCHEMBL10133785 0.71 NR1H3 (0.48) NR1H3P2RX4MAPTLMNANPSR1
SCHEMBL12776322 0.70 MAPT (0.38) P2RX4MAPTKMT2AMEN1LMNA
SCHEMBL18596813 0.70 CYP11B1 (0.42) NR1H3MAPTKMT2AMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20150129861-A1 ORGANIC MATERIAL FOR DEPOSITION, AND ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, DEPOSITION METHOD, AND MANUFACTURING METHOD FOR ORGANIC PHOTOELECTRONIC ONVERSION ELEMENT OBTAINED USING THE SAME FUJIFILM CORPORATION (JP) 2015-05-14 US disclosed
US-20140042411-A1 METHOD FOR PURIFYING ORGANIC MATERIAL, MATERIAL FOR ORGANIC ELECTRONICS, PHOTOELECTRIC CONVERSION DEVICE, OPTICAL SENSOR, IMAGING DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2014-02-13 US disclosed