SCHEMBL2607158

SCHEMBL2607158

CN1c2ccccc2C=Cc2ccccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
KMT2A Q03164 4/20 0.49
MEN1 O00255 3/20 0.49
NPSR1 Q6W5P4 3/20 0.49
LMNA P02545 2/20 0.49
THRB P10828 1/20 0.49
MAOA P21397 1/20 0.48
P2RX4 Q99571 7/20 0.47
MAPK1 P28482 3/20 0.46
TSHR P16473 1/20 0.46
SCN4A P35499 1/20 0.46
SCN5A Q14524 1/20 0.46
SCN9A Q15858 1/20 0.46
P2RX1 P51575 3/20 0.45
P2RX3 P56373 3/20 0.45
P2RX7 Q99572 2/20 0.45
SMN1; SMN2 Q16637 4/20 0.45
GAA P10253 1/20 0.45
MTNR1A P48039 2/20 0.44
MTNR1B P49286 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10105334 0.84 MAPT (0.42) MAPTKMT2AMEN1NPSR1LMNA
SCHEMBL17187258 0.83 MAOA (0.48) MAPTKMT2AMEN1NPSR1LMNA
SCHEMBL12793382 0.83 MAPT (0.40) MAPTKMT2AMEN1NPSR1LMNA
SCHEMBL12841613 0.83 MEN1 (0.44) MAPTKMT2AMEN1NPSR1LMNA
SCHEMBL19885348 0.83 MAPT (0.44) MAPTKMT2AMEN1NPSR1LMNA
SCHEMBL13511705 0.82 MEN1 (0.39) MAPTKMT2AMEN1NPSR1LMNA
SCHEMBL12776322 0.80 MAPT (0.38) MAPTKMT2AMEN1NPSR1LMNA
SCHEMBL1102446 0.79 NR1H3 (0.42) MAPTKMT2AMEN1NPSR1LMNA
SCHEMBL15469131 0.79 NR1H3 (0.46) MAPTKMT2AMEN1NPSR1LMNA
SCHEMBL28148118 0.79 SMN1; SMN2 (0.43) MAPTKMT2AMEN1NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240224547-A1 PEROVSKITE PHOTODIODE AND IMAGE SENSOR AND ELECTRONIC DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-04 US disclosed
US-12022725-B2 Electronic device, light-emitting device, electronic appliance, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-06-25 US disclosed
US-12022725-B2 Electronic device, light-emitting device, electronic appliance, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-06-25 US disclosed
US-20240074308-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
US-20240074308-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-02-29 US disclosed
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 HIROSHIMA UNIVERSITY (JP) 2024-01-25 US disclosed
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 HIROSHIMA UNIVERSITY (JP) 2024-01-25 US disclosed
US-11840550-B2 Silyl-biaryl phosphoramidites and methods of making BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-12-12 US disclosed
US-20230380274-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-23 US disclosed
US-11758808-B2 Ortho-substituted thermally activated delayed fluorescence material and organic light-emitting device comprising same SAMSUNG DISPLAY CO., LTD. (KR) 2023-09-12 US disclosed
US-20070259208-A1 Electroluminescent materials and devices MERCK PATENT GMBH (DE) 2007-11-08 US disclosed
US-20070200096-A1 Doped lithium quinolate OLED-T LIMITED (GB) 2007-08-30 US disclosed
US-20070200096-A1 Doped lithium quinolate OLED-T LIMITED (GB) 2007-08-30 US disclosed
WO-2007080116-A2 USE OF CNS PENETRATING ANTICANCER COMPOUNDS FOR THE TREATMENT OF PROTOZAN DISEASES DORMEYER MATTHIAS (DE) 2007-07-19 WO disclosed
EP-1808173-A1 Use of CNS penetrating anticancer compounds for the treatment of protozan diseases Dormeyer, Matthias (DE) 2007-07-18 EP disclosed
US-20070135502-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE BACH ANDREW T 2007-06-14 US disclosed
US-7183304-B2 such as (R)-1-{4-[4-(4-Phenoxy-2-propyl-phenoxy)-butoxy]-benzenesulfonyl}-azetidine-2-carboxylic acid, used as peroxisome proliferator-activated receptor agonists; hypoglycemic agents NOVARTIS AG (CH) 2007-02-27 US disclosed
US-20070003788-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003788-A1 Organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2007-01-04 US disclosed
US-20070004704-A1 Such as 6-Methyl-2-[4-(5-methyl-2-phenyl-oxazol-4-ylmethoxy)-benzenesulfonylamino]-benzoic acid which binds Peroxisome Proliferator-Activated Receptors; conditions in which impaired glucose tolerance, hyperglycemia and insulin resistance are implicated, such as type-1 and type-2 diabetes, and Syndrome X NOVARTIS AG (CH) 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840550-B2 Silyl-biaryl phosphoramidites and methods of making PAICS, PGLS, SCLY MAPT 3825/4885KMT2A 1728/4885MEN1 1703/4885
US-12022725-B2 Electronic device, light-emitting device, electronic appliance, and lighting device EED, L1CAM, ALDH1A2 MAPT 1989/4885KMT2A 461/4885MEN1 1223/4885
US-20070135502-A1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE PPARG, PPARA, PPARD MAPT 3328/4885KMT2A 2522/4885MEN1 3603/4885
US-20230380274-A1 ORTHO-SUBSTITUTED THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME TEAD2, TEAD3, TEAD4 MAPT 756/4885KMT2A 2414/4885MEN1 4665/4885
US-20070004704-A1 Such as 6-Methyl-2-[4-(5-methyl-2-phenyl-oxazol-4-ylmethoxy)-benzenesulfonylamino]-benzoic acid which binds Peroxisome Proliferator-Activated Receptors; conditions in which impaired glucose tolerance, hyperglycemia and insulin resistance are implicated, such as type-1 and type-2 diabetes, and Syndrome X PPARG, GPR119, PPARA MAPT 2511/4885KMT2A 1633/4885MEN1 3853/4885
US-11758808-B2 Ortho-substituted thermally activated delayed fluorescence material and organic light-emitting device comprising same TEAD2, TEAD3, TEAD4 MAPT 756/4885KMT2A 2414/4885MEN1 4665/4885
US-20240024266-A1 Therapeutic Agent or Prophylactic Agent for COVID-19 PIN1, ACE2, ACE MAPT 261/4885KMT2A 3733/4885MEN1 3457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.