Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114741 | 0.79 | APP (0.92) | APPMAPTKCNH2CA12CA1 | |
| SCHEMBL10331893 | 0.78 | CYP1A1 (0.48) | APPMAPTCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL55166 | 0.76 | — | — | |
| Diphenylacetylene SCHEMBL68254 | 0.76 | APP (1.00) | APPMAPTKCNH2CA12CA1 | |
| Diphenylacetylene SCHEMBL960609 | 0.76 | APP (1.00) | APPMAPTKCNH2CA12CA1 | |
| Diphenylacetylene SCHEMBL29188592 | 0.76 | APP (1.00) | APPMAPTKCNH2CA12CA1 | |
| Diphenylacetylene SCHEMBL23754283 | 0.73 | APP (0.80) | APPMAPTKCNH2CA12CA1 | |
| SCHEMBL14875991 | 0.73 | TSHR (0.37) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3796509 | 0.73 | APP (0.80) | APPMAPTKCNH2CA12CA1 | |
| Hydrochloric Acid SCHEMBL11803910 | 0.73 | TSHR (0.37) | MAPTCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140046084-A1 | Siloxane Compound and Cured Product Thereof | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-02-13 | — | — | US | disclosed |
| US-20140046014-A1 | SILOXANE COMPOUND AND CURED PRODUCT THEREOF | CENTRAL GLASS COMPANY, LIMITED (JP) | 2014-02-13 | — | — | US | disclosed |