SCHEMBL15469341

SCHEMBL15469341

CC1(C)c2ccccc2-c2ccc(N3c4ccc(-c5ccc6cc(-c7ccccc7)ccc6c5)cc4C(C)(C)c4cc(-c5ccc6cc(-c7ccccc7)ccc6c5)ccc43)cc21

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 9/20 0.39
AR P10275 1/20 0.35
PGR P06401 7/20 0.35
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
PDE6D O43924 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13827550 0.95 PDK2 (0.43) PDK2ARPGR
SCHEMBL15464025 0.95 PDK2 (0.43) PDK2ARPGR
SCHEMBL15469299 0.95 PDK2 (0.43) PDK2ARPGR
SCHEMBL15469336 0.95 PDK2 (0.43) PDK2ARPGR
SCHEMBL15469298 0.95 PDK2 (0.43) PDK2ARPGR
SCHEMBL15469300 0.94 PDK2 (0.39) PDK2ARPGRPDE6D
SCHEMBL15469338 0.94 PDK2 (0.39) PDK2ARPGRPDE6D
SCHEMBL15469339 0.94 AR (0.35) PDK2ARPGRESR1ESR2
SCHEMBL13827878 0.93 PDK2 (0.41) PDK2ARPGRPDE6D
SCHEMBL16547127 0.92 AKT1 (0.34) PDK2ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905770-B2 Compound having acridan ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
US-9905770-B2 Compound having acridan ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
EP-2703388-A1 COMPOUND WITH ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2014-03-05 EP disclosed
US-20140042425-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed
US-20140042425-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed