SCHEMBL15469339

SCHEMBL15469339

CC1(C)c2ccccc2-c2ccc(N3c4ccc(-c5ccc6ccccc6c5)cc4C(C)(C)c4cc(-c5ccc6ccccc6c5)ccc43)cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.35
LPL P06858 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
HPGD P15428 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
PGR P06401 7/20 0.34
POLB P06746 1/20 0.34
KMT2A Q03164 1/20 0.34
PDK2 Q15119 2/20 0.33
HSP90AA1 P07900 1/20 0.33
AKT1 P31749 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16547127 0.98 AKT1 (0.34) ARLPLLIPGALDH1A1LMNA
SCHEMBL15469337 0.96 ALDH1A1 (0.38) ARLPLLIPGALDH1A1LMNA
SCHEMBL15469341 0.94 PDK2 (0.39) ARPGRPDK2ESR1ESR2
SCHEMBL15469338 0.93 PDK2 (0.39) ARLPLLIPGALDH1A1LMNA
SCHEMBL15469300 0.93 PDK2 (0.39) ARLPLLIPGALDH1A1LMNA
SCHEMBL15469292 0.92 PIM1 (0.34) ARALDH1A1LMNAHPGDCYP1A2
SCHEMBL15469287 0.92 AR (0.39) ARPGRKMT2APDK2
SCHEMBL13557593 0.90 AR (0.37) ARPGRKMT2APDK2
SCHEMBL19381066 0.89 ALDH1A1 (0.36) ARLPLLIPGALDH1A1LMNA
SCHEMBL15469299 0.88 PDK2 (0.43) ARPGRPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905770-B2 Compound having acridan ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
US-9905770-B2 Compound having acridan ring structure, and organic electroluminescent device HODOGAYA CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
EP-2703388-A1 COMPOUND WITH ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2014-03-05 EP disclosed
US-20140042425-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed
US-20140042425-A1 COMPOUND HAVING ACRIDAN RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2014-02-13 US disclosed