SCHEMBL15469675

SCHEMBL15469675

CCCCc1c(Cc2ccc(-c3ccccc3-c3noc(=O)[nH]3)cc2)c(=O)n(C2CCC(OC(=O)C(C)(C)O)CC2)c2ccnn12

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC33A1 O00400 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15473328 1.00 SLC33A1 (0.84) SLC33A1
SCHEMBL1374086 0.96 SLC33A1 (0.84) SLC33A1
SCHEMBL1374083 0.96 SLC33A1 (0.84) SLC33A1
SCHEMBL12148315 0.96 SLC33A1 (0.84) SLC33A1
SCHEMBL1374322 0.92 SLC33A1 (1.00) SLC33A1
SCHEMBL12148330 0.92 SLC33A1 (1.00) SLC33A1
SCHEMBL1374320 0.92 SLC33A1 (1.00) SLC33A1
SCHEMBL15473318 0.91 SLC33A1 (0.80) SLC33A1
SCHEMBL15469670 0.91 SLC33A1 (0.80) SLC33A1
SCHEMBL13080611 0.90 SLC33A1 (0.77) SLC33A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140046056-A1 FUSED RING COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140046056-A1 FUSED RING COMPOUND AND USE THEREOF PPARA, PPARG, AGTR2 SLC33A1 985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.