SCHEMBL15470253

SCHEMBL15470253

c1ccc(-c2ccc(-c3ccc4c(c3)N(c3ccccc3)c3ccccc3N4c3ccc(-c4ccc(-c5ccc6sc7ccccc7c6c5)cc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.38
PIM3 Q86V86 1/20 0.38
LIMK1 P53667 1/20 0.36
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
CYP1A2 P05177 1/20 0.35
FAAH O00519 3/20 0.34
MGLL Q99685 3/20 0.34
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
PTPN7 P35236 1/20 0.33
DUSP3 P51452 1/20 0.33
PTPN12 Q05209 1/20 0.33
PTPN22 Q9Y2R2 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PDE6D O43924 1/20 0.33
ROCK1 Q13464 1/20 0.32
HSP90AA1 P07900 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470249 0.96 PIM3 (0.37) GPR3PIM3LIMK1TNKSTNKS2
SCHEMBL15470245 0.94 GPR3 (0.42) GPR3PIM3LIMK1TNKSTNKS2
SCHEMBL15470252 0.90 PIM3 (0.38) GPR3PIM3LIMK1TNKSTNKS2
SCHEMBL15470247 0.90 PIM3 (0.36) GPR3PIM3LIMK1TNKSTNKS2
SCHEMBL15470078 0.89 GPR3 (0.33) GPR3PIM3LIMK1CYP1A2ALDH1A1
SCHEMBL15470484 0.88 GPR3 (0.33) GPR3PIM3LIMK1TNKSTNKS2
SCHEMBL16884819 0.85 PIM3 (0.40) GPR3PIM3LIMK1TNKSTNKS2
SCHEMBL15470205 0.85 PIM3 (0.37) GPR3PIM3LIMK1TNKSTNKS2
SCHEMBL15470109 0.85 PDE6D (0.32) PDE6D
SCHEMBL15470214 0.85 HDAC6 (0.38) GPR3PIM3LIMK1TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed