SCHEMBL15470259

SCHEMBL15470259

c1ccc2c(c1)Oc1ccccc1N2c1ccc(-c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.49
PRKDC P78527 5/20 0.42
GGPS1 O95749 1/20 0.37
PIK3CD O00329 1/20 0.36
PIK3CB P42338 1/20 0.36
ADK P55263 1/20 0.35
ATM Q13315 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.35
PRMT5 O14744 1/20 0.33
WDR77 Q9BQA1 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.32
CYP2C19 P33261 1/20 0.32
KMT2A Q03164 1/20 0.32
PDE6D O43924 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
CDC14B O60729 1/20 0.31
CDC14A Q9UNH5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21157169 0.92 ALOX5 (0.38) ALOX5PRKDCPIK3CDPIK3CBATM
SCHEMBL17278494 0.91 ALOX5 (0.42) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL15470262 0.91 ALOX5 (0.44) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL13827274 0.90 ALOX5 (0.48) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL17278492 0.89 ALOX5 (0.39) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL15470261 0.87 ALOX5 (0.47) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL15470327 0.86 ALOX5 (0.51) ALOX5PRKDCGGPS1PIK3CDPIK3CB
SCHEMBL15470411 0.86 ALOX5 (0.41) ALOX5PRKDCGGPS1ATMPTGES2
SCHEMBL15470263 0.86 ALOX5 (0.46) ALOX5PRKDCGGPS1ATMPTGES2
SCHEMBL15470412 0.85 ALOX5 (0.40) ALOX5PRKDCGGPS1PIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed