SCHEMBL15470422

SCHEMBL15470422

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5c(c4)N(c4ccccc4)c4ccccc4N5c4ccc(-c5cccc6c5oc5ccccc56)cc4)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
PRKDC P78527 8/20 0.38
GGPS1 O95749 1/20 0.36
PTGES2 Q9H7Z7 1/20 0.34
PDE6D O43924 1/20 0.33
PRMT5 O14744 1/20 0.32
WDR77 Q9BQA1 1/20 0.32
ATM Q13315 1/20 0.32
ALDH1A1 P00352 3/20 0.32
PIK3CD O00329 2/20 0.32
PIK3CA P42336 2/20 0.32
PIK3CB P42338 2/20 0.32
PIK3CG P48736 2/20 0.32
KDM4E B2RXH2 2/20 0.32
BRD4 O60885 2/20 0.32
BRD2 P25440 2/20 0.32
BRD3 Q15059 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
PDE2A O00408 1/20 0.32
PIK3C2A O00443 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470481 0.97 ALOX5 (0.44) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL15470330 0.94 ALOX5 (0.48) ALOX5PRKDCGGPS1PTGES2PDE6D
SCHEMBL15470421 0.93 ALOX5 (0.44) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL18776244 0.91 ALOX5 (0.42) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL15470427 0.89 ALOX5 (0.34) ALOX5PRKDCPLA2G2APLA2G4A
SCHEMBL15469925 0.88 ALOX5 (0.40) ALOX5PRKDCGGPS1PTGES2PRMT5
SCHEMBL15470412 0.88 ALOX5 (0.40) ALOX5PRKDCGGPS1PTGES2PDE6D
SCHEMBL15470327 0.87 ALOX5 (0.51) ALOX5PRKDCGGPS1PTGES2PDE6D
SCHEMBL15470122 0.86 ALOX5 (0.36) ALOX5PRKDC
SCHEMBL15469876 0.86 ALOX5 (0.40) ALOX5PRKDCGGPS1PTGES2ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed
US-20140042412-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC LIGHT-EMITTING DIODE INCLUDING THE SAME AND DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT-EMITTING DIODE CHEIL INDUSTRIES, INC. (KR) 2014-02-13 US disclosed