Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MPI | P34949 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445518 | 0.96 | PDK2 (0.37) | PDK2PTPN1 | |
| SCHEMBL15470691 | 0.95 | HTT (0.32) | HTTALDH1A1TP53LMNA | |
| SCHEMBL15470692 | 0.95 | HTT (0.32) | HTTALDH1A1TP53LMNA | |
| SCHEMBL17479893 | 0.94 | HTT (0.31) | HTTTP53 | |
| SCHEMBL13824178 | 0.94 | TP53 (0.33) | PDK2HTTALDH1A1TP53LMNA | |
| SCHEMBL15445521 | 0.94 | HTT (0.32) | HTTALDH1A1TP53LMNA | |
| SCHEMBL13824173 | 0.93 | HTT (0.33) | HTT | |
| SCHEMBL15445493 | 0.92 | PDK2 (0.31) | PDK2HTTTP53 | |
| SCHEMBL14232865 | 0.92 | HTT (0.31) | HTTTP53 | |
| SCHEMBL22239340 | 0.92 | ALK (0.32) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217812-B2 | Photochromic polymer | VIVIMED LABS EUROPE LTD (GB) | 2015-12-22 | — | — | US | disclosed |
| US-9217812-B2 | Photochromic polymer | VIVIMED LABS EUROPE LTD (GB) | 2015-12-22 | — | — | US | disclosed |
| US-20140042377-A1 | Photochromic Polymer | VIVIMED LABS EUROPE LTD (GB) | 2014-02-13 | — | — | US | disclosed |
| US-20140042377-A1 | Photochromic Polymer | VIVIMED LABS EUROPE LTD (GB) | 2014-02-13 | — | — | US | disclosed |