SCHEMBL15470895

SCHEMBL15470895

COC(=O)C(=C1c2ccccc2Sc2ccccc21)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
TSHR P16473 1/20 0.42
HPGD P15428 2/20 0.41
POLB P06746 2/20 0.41
HTT P42858 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP3A4 P08684 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
BCHE P06276 7/20 0.41
ACHE P22303 3/20 0.38
PLEC Q15149 1/20 0.37
SLC6A3 Q01959 1/20 0.36
SRC P12931 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17122115 0.85 TSHR (0.48) MAPTTSHRHPGDPOLBHTT
SCHEMBL15470902 0.82 TSHR (0.40) MAPTTSHRHPGDPOLBHTT
SCHEMBL15470961 0.82 BCHE (0.46) MAPTHPGDPOLBHTTKDM4E
SCHEMBL15470888 0.81 MAPT (0.47) MAPTTSHRHPGDPOLBHTT
SCHEMBL21908167 0.79 BCHE (0.44) MAPTHPGDPOLBHTTKDM4E
SCHEMBL25058860 0.75 BCHE (0.41) MAPTHPGDPOLBHTTKDM4E
SCHEMBL15470955 0.74 IDO1 (0.57) MAPTHPGDPOLBHTTKDM4E
SCHEMBL18697397 0.72 BCHE (0.41) MAPTHPGDPOLBHTTKDM4E
SCHEMBL23209617 0.70 BCHE (0.36) MAPTHPGDPOLBHTTKDM4E
SCHEMBL15470912 0.69 MAPT (0.49) MAPTTSHRHTTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9926289-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2018-03-27 US disclosed
US-9765051-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-09-19 US disclosed
US-9650356-B2 2017-05-16 US disclosed
US-9611246-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-04-04 US disclosed
US-20160024046-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160022555-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160002200-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-07 US disclosed
US-9145383-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2015-09-29 US disclosed
US-20140044654-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES HALLSTAR INNOVATIONS CORP. (US) 2014-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160024046-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN MAPT 2772/4885TSHR 4095/4885HPGD 176/4885
US-20160002200-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN MAPT 2772/4885TSHR 4095/4885HPGD 176/4885
US-20140044654-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN MAPT 2772/4885TSHR 4095/4885HPGD 176/4885
US-20160022555-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN MAPT 2772/4885TSHR 4095/4885HPGD 176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.