SCHEMBL15470912

SCHEMBL15470912

COC(=O)/C(=C1\c2ccccc2C(=O)c2c1ccc1ccccc21)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.49
MEN1 O00255 5/20 0.49
KMT2A Q03164 5/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
RAB9A P51151 3/20 0.49
ALDH1A1 P00352 2/20 0.49
DNMT1 P26358 1/20 0.48
MITF O75030 1/20 0.38
NSD2 O96028 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
HKDC1 Q2TB90 1/20 0.37
CYP3A4 P08684 3/20 0.37
MMP14 P50281 2/20 0.36
WDR5 P61964 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
CYP1A2 P05177 4/20 0.36
CYP2C9 P11712 3/20 0.36
CYP2C19 P33261 3/20 0.36
CYP2D6 P10635 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15470917 0.86 MAPT (0.47) MAPTMEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL15470888 0.83 MAPT (0.47) MAPTMEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL17122115 0.78 TSHR (0.48) MAPTMEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL15600073 0.73 DNMT1 (0.51) MAPTMEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL15470913 0.73 DNMT1 (0.51) MAPTMEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL15600030 0.73 DNMT1 (0.48) MAPTMEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL15470916 0.73 DNMT1 (0.48) MAPTMEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL2175783 0.70 DNMT1 (0.92) MAPTMEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL29440308 0.70 DNMT1 (0.92) MAPTMEN1KMT2ASMN1; SMN2RAB9A
SCHEMBL30375875 0.70 DNMT1 (0.92) MAPTMEN1KMT2ASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9926289-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2018-03-27 US disclosed
US-9765051-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-09-19 US disclosed
US-9650356-B2 2017-05-16 US disclosed
US-9611246-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-04-04 US disclosed
US-20160022555-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160024046-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160002200-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-07 US disclosed
US-9145383-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2015-09-29 US disclosed
US-20140044654-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES HALLSTAR INNOVATIONS CORP. (US) 2014-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160024046-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN MAPT 2772/4885MEN1 2120/4885KMT2A 3727/4885
US-20160002200-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN MAPT 2772/4885MEN1 2120/4885KMT2A 3727/4885
US-20140044654-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN MAPT 2772/4885MEN1 2120/4885KMT2A 3727/4885
US-20160022555-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN MAPT 2772/4885MEN1 2120/4885KMT2A 3727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.