SCHEMBL15470903

SCHEMBL15470903

COC(=O)C(C(=O)c1ccccc1)=C1c2ccccc2Oc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
CES2 O00748 5/20 0.40
CES1 P23141 5/20 0.40
P2RX4 Q99571 2/20 0.40
CYP3A4 P08684 2/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 3/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HPGD P15428 1/20 0.37
ALOX5 P09917 1/20 0.37
SLC6A3 Q01959 1/20 0.36
ALDH1A1 P00352 1/20 0.36
IDO1 P14902 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16804201 0.89 P2RX4 (0.47) P2RX4KMT2AALOX5ALDH1A1IDO1
SCHEMBL15470876 0.87 TSHR (0.46) TSHRCES2CES1MAPTMEN1
SCHEMBL15470893 0.83 MAPT (0.47) TSHRCES2CES1CYP3A4CYP1A2
SCHEMBL15470902 0.81 TSHR (0.40) TSHRCES2CES1MAPTHPGD
SCHEMBL15470927 0.79 GPR3 (0.42) TSHRCES2CES1MEN1KMT2A
SCHEMBL15470921 0.78 TSHR (0.38) TSHRCES2CES1MAPTSMN1; SMN2
SCHEMBL42428 0.76 TSHR (0.60) TSHRCES2CES1CYP3A4MAPT
Benzene SCHEMBL28195988 0.76 TSHR (0.60) TSHRCES2CES1CYP3A4MAPT
SCHEMBL21908165 0.76 P2RX4 (0.45) P2RX4MAPTMEN1KMT2AALOX5
SCHEMBL15470937 0.74 IDO1 (0.41) TSHRCYP3A4CYP1A2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9926289-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2018-03-27 US disclosed
US-9765051-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-09-19 US disclosed
US-9650356-B2 2017-05-16 US disclosed
US-9611246-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2017-04-04 US disclosed
US-20160024046-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160022555-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-28 US disclosed
US-20160002200-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES BANK OF AMERICA, N.A., AS ADMINISTRATIVE AGENT 2016-01-07 US disclosed
US-9145383-B2 Compositions, apparatus, systems, and methods for resolving electronic excited states HALLSTAR INNOVATIONS CORP. (US) 2015-09-29 US disclosed
US-20140044654-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES HALLSTAR INNOVATIONS CORP. (US) 2014-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160024046-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN TSHR 4095/4885CES2 1265/4885CES1 2679/4885
US-20160002200-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN TSHR 4095/4885CES2 1265/4885CES1 2679/4885
US-20140044654-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN TSHR 4095/4885CES2 1265/4885CES1 2679/4885
US-20160022555-A1 COMPOSITIONS, APPARATUS, SYSTEMS, AND METHODS FOR RESOLVING ELECTRONIC EXCITED STATES RECQL, BLM, WRN TSHR 4095/4885CES2 1265/4885CES1 2679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.